Selective oestrogen receptor modulators lasofoxifene and bazedoxifene inhibit joint inflammation and osteoporosis in ovariectomised mice with collagen-induced arthritis

Objective. RA predominantly affects post-menopausal women and is strongly associated with development of generalised osteoporosis. To find treatments that target both joint manifestations and osteoporosis in RA is desirable. The third generation of selective oestrogen receptor modulators (SERMs) [la...

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Detalles Bibliográficos
Autores principales: Andersson, Annica, Bernardi, Angelina I., Stubelius, Alexandra, Nurkkala-Karlsson, Merja, Ohlsson, Claes, Carlsten, Hans, Islander, Ulrika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746431/
https://www.ncbi.nlm.nih.gov/pubmed/26424839
http://dx.doi.org/10.1093/rheumatology/kev355

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