RNF135, RING finger protein, promotes the proliferation of human glioblastoma cells in vivo and in vitro via the ERK pathway

Ring finger protein 135 (RNF135), located on chromosome 17q11.2, is a RING finger domain-containing E3 ubiquitin ligase that was identified as a bio-marker and therapy target of glioblastoma. In our study, we confirmed that RNF135 was up-regulated in glioblastoma tissues compared with normal brain (...

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Detalles Bibliográficos
Autores principales: Liu, Yongjian, Wang, Feng, Liu, Yongsheng, Yao, Yiqun, Lv, Xiupeng, Dong, Bin, Li, Jun, Ren, Siyang, Yao, Yiwen, Xu, Yinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746631/
https://www.ncbi.nlm.nih.gov/pubmed/26856755
http://dx.doi.org/10.1038/srep20642

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