Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2

Shelterin protein TRF2 modulates telomere structures by promoting dsDNA compaction and T-loop formation. Advancement of our understanding of the mechanism underlying TRF2-mediated DNA compaction requires additional information regarding DNA paths in TRF2-DNA complexes. To uncover the location of DNA...

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Detalles Bibliográficos
Autores principales: Kaur, Parminder, Wu, Dong, Lin, Jiangguo, Countryman, Preston, Bradford, Kira C., Erie, Dorothy A., Riehn, Robert, Opresko, Patricia L., Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746636/
https://www.ncbi.nlm.nih.gov/pubmed/26856421
http://dx.doi.org/10.1038/srep20513

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