Cargando…
Plumericin inhibits proliferation of vascular smooth muscle cells by blocking STAT3 signaling via S-glutathionylation
The etiology of atherosclerosis and restenosis involves aberrant inflammation and proliferation, rendering compounds with both anti-inflammatory and anti-mitogenic properties as promising candidates for combatting vascular diseases. A recent study identified the iridoid plumericin as a new scaffold...
Autores principales: | Heiss, Elke H, Liu, Rongxia, Waltenberger, Birgit, Khan, Shafaat, Schachner, Daniel, Kollmann, Paul, Zimmermann, Kristin, Cabaravdic, Muris, Uhrin, Pavel, Stuppner, Hermann, Breuss, Johannes M, Atanasov, Atanas G, Dirsch, Verena M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746734/ https://www.ncbi.nlm.nih.gov/pubmed/26858089 http://dx.doi.org/10.1038/srep20771 |
Ejemplares similares
-
Nonprenylated Xanthones from Gentiana lutea, Frasera caroliniensis, and Centaurium erythraea as Novel Inhibitors of Vascular Smooth Muscle Cell Proliferation
por: Waltenberger, Birgit, et al.
Publicado: (2015) -
Identification of plumericin as a potent new inhibitor of the NF-κB pathway with anti-inflammatory activity in vitro and in vivo
por: Fakhrudin, N, et al.
Publicado: (2014) -
Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin
por: Khan, Shafaat Y., et al.
Publicado: (2017) -
Xanthohumol Blocks Proliferation and Migration of
Vascular Smooth Muscle Cells in Vitro and Reduces
Neointima Formation in Vivo
por: Liu, Rongxia, et al.
Publicado: (2017) -
Capsaicin from chili (
Capsicum spp.) inhibits vascular smooth muscle cell proliferation
por: Liu, Rongxia, et al.
Publicado: (2015)