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A group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors

BACKGROUND: Previously, we applied basic group theory and related concepts to scales of measurement of clinical disease states and clinical findings (including laboratory data). To gain a more concrete comprehension, we here apply the concept of matrix representation, which was not explicitly exploi...

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Autores principales: Sawamura, Jitsuki, Morishita, Shigeru, Ishigooka, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746825/
https://www.ncbi.nlm.nih.gov/pubmed/26856979
http://dx.doi.org/10.1186/s12976-016-0031-8
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author Sawamura, Jitsuki
Morishita, Shigeru
Ishigooka, Jun
author_facet Sawamura, Jitsuki
Morishita, Shigeru
Ishigooka, Jun
author_sort Sawamura, Jitsuki
collection PubMed
description BACKGROUND: Previously, we applied basic group theory and related concepts to scales of measurement of clinical disease states and clinical findings (including laboratory data). To gain a more concrete comprehension, we here apply the concept of matrix representation, which was not explicitly exploited in our previous work. METHODS: Starting with a set of orthonormal vectors, called the basis, an operator R(j) (an N-tuple patient disease state at the j-th session) was expressed as a set of stratified vectors representing plural operations on individual components, so as to satisfy the group matrix representation. RESULTS: The stratified vectors containing individual unit operations were combined into one-dimensional square matrices [R(j)]s. The [R(j)]s meet the matrix representation of a group (ring) as a K-algebra. Using the same-sized matrix of stratified vectors, we can also express changes in the plural set of [R(j)]s. The method is demonstrated on simple examples. CONCLUSIONS: Despite the incompleteness of our model, the group matrix representation of stratified vectors offers a formal mathematical approach to clinical medicine, aligning it with other branches of natural science.
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spelling pubmed-47468252016-02-10 A group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors Sawamura, Jitsuki Morishita, Shigeru Ishigooka, Jun Theor Biol Med Model Research BACKGROUND: Previously, we applied basic group theory and related concepts to scales of measurement of clinical disease states and clinical findings (including laboratory data). To gain a more concrete comprehension, we here apply the concept of matrix representation, which was not explicitly exploited in our previous work. METHODS: Starting with a set of orthonormal vectors, called the basis, an operator R(j) (an N-tuple patient disease state at the j-th session) was expressed as a set of stratified vectors representing plural operations on individual components, so as to satisfy the group matrix representation. RESULTS: The stratified vectors containing individual unit operations were combined into one-dimensional square matrices [R(j)]s. The [R(j)]s meet the matrix representation of a group (ring) as a K-algebra. Using the same-sized matrix of stratified vectors, we can also express changes in the plural set of [R(j)]s. The method is demonstrated on simple examples. CONCLUSIONS: Despite the incompleteness of our model, the group matrix representation of stratified vectors offers a formal mathematical approach to clinical medicine, aligning it with other branches of natural science. BioMed Central 2016-02-09 /pmc/articles/PMC4746825/ /pubmed/26856979 http://dx.doi.org/10.1186/s12976-016-0031-8 Text en © Sawamura et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Sawamura, Jitsuki
Morishita, Shigeru
Ishigooka, Jun
A group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors
title A group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors
title_full A group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors
title_fullStr A group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors
title_full_unstemmed A group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors
title_short A group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors
title_sort group matrix representation relevant to scales of measurement of clinical disease states via stratified vectors
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746825/
https://www.ncbi.nlm.nih.gov/pubmed/26856979
http://dx.doi.org/10.1186/s12976-016-0031-8
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