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Evaluation of TgH(CX3CR1-EGFP) mice implanted with mCherry-GL261 cells as an in vivo model for morphometrical analysis of glioma-microglia interaction

BACKGROUND: Glioblastoma multiforme is the most aggressive brain tumor. Microglia are prominent cells within glioma tissue and play important roles in tumor biology. This work presents an animal model designed for the study of microglial cell morphology in situ during gliomagenesis. It also allows a...

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Detalles Bibliográficos
Autores principales:	Resende, Fernando F. B., Bai, Xianshu, Del Bel, Elaine Aparecida, Kirchhoff, Frank, Scheller, Anja, Titze-de-Almeida, Ricardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746826/ https://www.ncbi.nlm.nih.gov/pubmed/26856327 http://dx.doi.org/10.1186/s12885-016-2118-3

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