Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells

We explored the potential of Smac mimetics, which antagonize Inhibitor of Apoptosis (IAP) proteins, for chemosensitization of neuroblastoma (NB). Here, we report that Smac mimetics, e.g. BV6, prime NB cells for chemotherapeutics including the topoisomerase II inhibitor doxorubicin (DOX) and vinca al...

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Detalles Bibliográficos
Autores principales: Czaplinski, Sebastian, Abhari, Behnaz Ahangarian, Torkov, Alica, SeggewiΔ, Dominik, Hugle, Manuela, Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research paper: Autophagy and Cell Death
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747171/
https://www.ncbi.nlm.nih.gov/pubmed/26575016

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