The proinflammatory LTB(4)/BLT1 signal axis confers resistance to TGF-β1-induced growth inhibition by targeting Smad3 linker region

Leukotriene B4 (LTB(4)) is a potent pro-inflammatory eicosanoid that is derived from arachidonic acid, and its signaling is known to have a tumor-promoting role in several cancer types. In this study, we investigated whether enhanced LTB(4) signaling confers resistance to the cytostatic transforming...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeon, Woo-Kwang, Choi, Jiyeon, Park, Seong Ji, Jo, Eun Ji, Lee, Young K., Lim, Seunghwan, Kim, Jae-Hong, Letterio, John J., Liu, Fang, Kim, Seong-Jin, Kim, Byung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747179/
https://www.ncbi.nlm.nih.gov/pubmed/26497676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747179/
https://www.ncbi.nlm.nih.gov/pubmed/26497676

Ejemplares similares