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The proinflammatory LTB(4)/BLT1 signal axis confers resistance to TGF-β1-induced growth inhibition by targeting Smad3 linker region

Leukotriene B4 (LTB(4)) is a potent pro-inflammatory eicosanoid that is derived from arachidonic acid, and its signaling is known to have a tumor-promoting role in several cancer types. In this study, we investigated whether enhanced LTB(4) signaling confers resistance to the cytostatic transforming...

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Detalles Bibliográficos
Autores principales:	Jeon, Woo-Kwang, Choi, Jiyeon, Park, Seong Ji, Jo, Eun Ji, Lee, Young K., Lim, Seunghwan, Kim, Jae-Hong, Letterio, John J., Liu, Fang, Kim, Seong-Jin, Kim, Byung-Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747179/ https://www.ncbi.nlm.nih.gov/pubmed/26497676

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