5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits

Despite marked tumor shrinkage after 5-FU treatment, the frequency of colon cancer relapse indicates that a fraction of tumor cells survives treatment causing tumor recurrence. The majority of cancer cells divert metabolites into anabolic pathways through Warburg behavior giving an advantage in term...

Descripción completa

Detalles Bibliográficos
Autores principales: Denise, Corti, Paoli, Paolo, Calvani, Maura, Taddei, Maria Letizia, Giannoni, Elisa, Kopetz, Scott, Kazmi, Syed Mohammad Ali, Pia, Morelli Maria, Pettazzoni, Piergiorgio, Sacco, Elena, Caselli, Anna, Vanoni, Marco, Landriscina, Matteo, Cirri, Paolo, Chiarugi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747183/
https://www.ncbi.nlm.nih.gov/pubmed/26527315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747183/
https://www.ncbi.nlm.nih.gov/pubmed/26527315

Ejemplares similares