Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance

Ras is aberrantly activated in many cancers and active DNA demethylation plays a fundamental role to establish DNA methylation pattern which is of importance to cancer development. However, it was unknown whether and how Ras regulate DNA demethylation during carcinogenesis. Here we found that Ras do...

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Detalles Bibliográficos
Autores principales: Sun, Jie, Shen, Qi, Lu, Haiqi, Jiang, Zhinong, Xu, Wenxia, Feng, Lifeng, Li, Ling, Wang, Xian, Cai, Xiujun, Jin, Hongchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747204/
https://www.ncbi.nlm.nih.gov/pubmed/26544625

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