Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma

Repeat tumor biopsies to study genomic changes during therapy are difficult, invasive and data are confounded by tumoral heterogeneity. The analysis of circulating tumor DNA (ctDNA) can provide a non-invasive approach to assess prognosis and the genetic evolution of tumors in response to therapy. Mu...

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Detalles Bibliográficos
Autores principales: Gray, Elin S., Rizos, Helen, Reid, Anna L., Boyd, Suzanah C., Pereira, Michelle R., Lo, Johnny, Tembe, Varsha, Freeman, James, Lee, Jenny H.J., Scolyer, Richard A., Siew, Kelvin, Lomma, Chris, Cooper, Adam, Khattak, Muhammad A., Meniawy, Tarek M., Long, Georgina V., Carlino, Matteo S., Millward, Michael, Ziman, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747205/
https://www.ncbi.nlm.nih.gov/pubmed/26524482

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