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Haloperidol Suppresses NF-kappaB to Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Response in RAW 264 Cells

BACKGROUND: Haloperidol, a tranquilizing agent, is administered both to treat symptoms of psychotic disorders and to sedate agitated and delirious patients. Notably, haloperidol has been suggested to inhibit the immune response through unknown mechanisms. We hypothesized that the sedative modulates...

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Detalles Bibliográficos
Autores principales: Yamamoto, Shunsuke, Ohta, Noriyuki, Matsumoto, Atsuhiro, Horiguchi, Yu, Koide, Moe, Fujino, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747317/
https://www.ncbi.nlm.nih.gov/pubmed/26842661
http://dx.doi.org/10.12659/MSM.895739