Efficacy of CDK4 inhibition against sarcomas depends on their levels of CDK4 and p16ink4 mRNA

Sarcomas are malignant tumors accounting for a high percentage of cancer morbidity and mortality in children and young adults. Surgery and radiation therapy are the accepted treatments for most sarcomas; however, patients with metastatic disease are treated with systemic chemotherapy. Many tumors di...

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Detalles Bibliográficos
Autores principales: Perez, Marco, Muñoz-Galván, Sandra, Jiménez-García, Manuel P., Marín, Juan J., Carnero, Amancio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747352/
https://www.ncbi.nlm.nih.gov/pubmed/26528855

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