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Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases
The activation of immune cells by targeting checkpoint inhibitors showed promising results with increased patient survival in distinct primary cancers. Since only limited data exist for human brain metastases, we aimed at characterizing tumor infiltrating lymphocytes (TILs) and expression of immune...
Autores principales: | Harter, Patrick N., Bernatz, Simon, Scholz, Alexander, Zeiner, Pia S., Zinke, Jenny, Kiyose, Makoto, Blasel, Stella, Beschorner, Rudi, Senft, Christian, Bender, Benjamin, Ronellenfitsch, Michael W., Wikman, Harriet, Glatzel, Markus, Meinhardt, Matthias, Juratli, Tareq A., Steinbach, Joachim P., Plate, Karl H., Wischhusen, Jörg, Weide, Benjamin, Mittelbronn, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747372/ https://www.ncbi.nlm.nih.gov/pubmed/26517811 |
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