Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin

Galectins are small soluble lectins that bind β-galactosides via their carbohydrate recognition domain (CRD). Their ability to dimerize is critical for the crosslinking of glycoprotein receptors and subsequent cellular signaling. This is particularly important in their immunomodulatory role via the...

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Detalles Bibliográficos
Autores principales: Vladoiu, Maria Claudia, Labrie, Marilyne, Létourneau, Myriam, Egesborg, Philippe, Gagné, Donald, Billard, Étienne, Grosset, Andrée-Anne, Doucet, Nicolas, Chatenet, David, St-Pierre, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747383/
https://www.ncbi.nlm.nih.gov/pubmed/26543238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747383/
https://www.ncbi.nlm.nih.gov/pubmed/26543238

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