The copy number of Epstein-Barr virus latent genome correlates with the oncogenicity by the activation level of LMP1 and NF-κB

A tumor model that Epstein-Barr virus (EBV) latent infection facilitated the tumorigenicity was previously established using the Maxi-EBV system. In the present approach, EBV-lost cell clones demonstrated significantly decreased tumorigenesis. On the other hand, the LMP1 gene in Maxi-EBV genome was...

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Detalles Bibliográficos
Autores principales: Zuo, Lielian, Yu, Haibo, Liu, Lingzhi, Tang, Yunlian, Wu, Hongzhuan, Yang, Jing, Zhu, Meijuan, Du, Shujuan, Zhao, Lian, Cao, Li, Li, Guiyuan, Lu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747387/
https://www.ncbi.nlm.nih.gov/pubmed/26517512

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