Inhibition of Eph receptor A4 by 2,5-dimethylpyrrolyl benzoic acid suppresses human pancreatic cancer growing orthotopically in nude mice

Ephrin receptor A4 (EphA4) is overexpressed in human pancreatic adenocarcinoma (PDAC) and activate cell growth. Recent studies have identified small molecules that block EphA4. In this study, we investigated the correlation between EphA4 expression and the prognosis of patients with PDAC. We also ex...

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Detalles Bibliográficos
Autores principales: Takano, Hironobu, Nakamura, Toru, Tsuchikawa, Takahiro, Kushibiki, Toshihiro, Hontani, Kouji, Inoko, Kazuho, Takahashi, Mizuna, Sato, Shoki, Abe, Hirotake, Takeuchi, Shintaro, Sato, Nagato, Hiraoka, Kei, Nishihara, Hiroshi, Shichinohe, Toshiaki, Hirano, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747390/
https://www.ncbi.nlm.nih.gov/pubmed/26516928

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