Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the US. Cancer-associated cachexia is present in up to 80% of PDAC patients and is associated with aggressive disease and poor prognosis. In the present studies we evaluated an anti-cancer natural product...

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Detalles Bibliográficos
Autores principales: Shukla, Surendra K., Dasgupta, Aneesha, Mehla, Kamiya, Gunda, Venugopal, Vernucci, Enza, Souchek, Joshua, Goode, Gennifer, King, Ryan, Mishra, Anusha, Rai, Ibha, Nagarajan, Sangeetha, Chaika, Nina V., Yu, Fang, Singh, Pankaj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747396/
https://www.ncbi.nlm.nih.gov/pubmed/26510913

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