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Heat Shock Protein 27 Plays a Pivotal Role in Myofibroblast Differentiation and in the Development of Bleomycin-Induced Pulmonary Fibrosis
Heat shock protein 27 (HSP27) is a member of the small molecular weight HSP family. Upon treatment with transforming growth factor β1 (TGF-β1), we observed upregulation of HSP27 along with that of α-smooth muscle actin (α-SMA), a marker of myofibroblast differentiation, in cultured human and mouse l...
Autores principales: | Park, Ah-Mee, Kanai, Kyosuke, Itoh, Tatsuki, Sato, Takao, Tsukui, Tatsuya, Inagaki, Yutaka, Selman, Moises, Matsushima, Kouji, Yoshie, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747463/ https://www.ncbi.nlm.nih.gov/pubmed/26859835 http://dx.doi.org/10.1371/journal.pone.0148998 |
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