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Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p

BACKGROUND: MicroRNAs (miRNAs) regulate gene expression by interfering translation or stability of target transcripts. This interplay between miRNA and their mRNA has been proposed as an important process in cancer development and progression. We have investigated molecular networks impacted by pred...

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Detalles Bibliográficos
Autores principales: Wotschofsky, Zofia, Gummlich, Linda, Liep, Julia, Stephan, Carsten, Kilic, Ergin, Jung, Klaus, Billaud, Jean-Noel, Meyer, Hellmuth-Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747468/
https://www.ncbi.nlm.nih.gov/pubmed/26859141
http://dx.doi.org/10.1371/journal.pone.0148746