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IL-15 Superagonist Expands mCD8(+ )T, NK and NKT Cells after Burn Injury but Fails to Improve Outcome during Burn Wound Infection
BACKGROUND: Severely burned patients are highly susceptible to opportunistic infections and sepsis, owing to the loss of the protective skin barrier and immunological dysfunction. Interleukin-15 (IL-15) belongs to the IL-2 family of common gamma chain cytokines and stimulates the proliferation and a...
Autores principales: | Patil, Naeem K., Luan, Liming, Bohannon, Julia K., Guo, Yin, Hernandez, Antonio, Fensterheim, Benjamin, Sherwood, Edward R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747596/ https://www.ncbi.nlm.nih.gov/pubmed/26859674 http://dx.doi.org/10.1371/journal.pone.0148452 |
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