Cargando…

Newcastle Disease Virus V Protein Targets Phosphorylated STAT1 to Block IFN-I Signaling

Newcastle disease virus (NDV) V protein is considered as an effector for IFN antagonism, however, the mechanism remains unknown. In this study, the expression of STAT1 and phospho-STAT1 in cells infected with NDV or transfected with V protein-expressing plasmids were analyzed. Our results showed tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiu, Xusheng, Fu, Qiang, Meng, Chunchun, Yu, Shengqing, Zhan, Yuan, Dong, Luna, Song, Cuiping, Sun, Yingjie, Tan, Lei, Hu, Shunlin, Wang, Xiaoquan, Liu, Xiaowen, Peng, Daxin, Liu, Xiufan, Ding, Chan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747598/ https://www.ncbi.nlm.nih.gov/pubmed/26859759 http://dx.doi.org/10.1371/journal.pone.0148560

Ejemplares similares

Amino Acid Mutations in Hemagglutinin-Neuraminidase Enhance the Virulence and Pathogenicity of the Genotype III Newcastle Disease Vaccine Strain After Intravenous Inoculation
por: Lu, Xiaolong, et al.
Publicado: (2022)

Deep Sequencing-Based Transcriptome Profiling Reveals Avian Interferon-Stimulated Genes and Provides Comprehensive Insight into Newcastle Disease Virus-Induced Host Responses
por: Liu, Weiwei, et al.
Publicado: (2018)

Strong innate immune response and cell death in chicken splenocytes infected with genotype VIId Newcastle disease virus
por: Hu, Zenglei, et al.
Publicado: (2012)

Rescue of virulent class I Newcastle disease virus variant 9a5b-D5C1
por: Yu, Yang, et al.
Publicado: (2012)

Chicken-derived MERTK protein inhibits Newcastle disease virus replication by increasing STAT1 phosphorylation in DF-1 cells
por: Tan, Lei, et al.
Publicado: (2023)

Newcastle Disease virus infection activates PI3K/Akt/mTOR and p38 MAPK/Mnk1 pathways to benefit viral mRNA translation via interaction of the viral NP protein and host eIF4E
por: Zhan, Yuan, et al.
Publicado: (2020)

Single-Cell Transcriptome Atlas of Newcastle Disease Virus in Chickens Both In Vitro and In Vivo
por: Liu, Weiwei, et al.
Publicado: (2023)

Characterization of virulent Newcastle disease viruses from vaccinated chicken flocks in Eastern China
por: Zhu, Jie, et al.
Publicado: (2016)

The M, F and HN genes of genotype VIId Newcastle disease virus are associated with the severe pathological changes in the spleen of chickens
por: Kai, Yan, et al.
Publicado: (2015)

Development of Strand-Specific Real-Time RT-PCR to Distinguish Viral RNAs during Newcastle Disease Virus Infection
por: Qiu, Xusheng, et al.
Publicado: (2014)

Comparison of the protective antigen variabilities of prevalent Newcastle disease viruses in response to homologous/heterologous genotype vaccines
por: Li, Yonghua, et al.
Publicado: (2021)

Activation of the PKR/eIF2α signaling cascade inhibits replication of Newcastle disease virus
por: Zhang, Shilei, et al.
Publicado: (2014)

Vitamin E Supplementation Ameliorates Newcastle Disease Virus-Induced Oxidative Stress and Alleviates Tissue Damage in the Brains of Chickens
por: Rehman, Zaib Ur, et al.
Publicado: (2018)

Biological Significance of Dual Mutations A494D and E495K of the Genotype III Newcastle Disease Virus Hemagglutinin-Neuraminidase In Vitro and In Vivo
por: Lu, Xiaolong, et al.
Publicado: (2022)

In Vitro and In Vivo Metabolomic Profiling after Infection with Virulent Newcastle Disease Virus
por: Liu, Panrao, et al.
Publicado: (2019)

Differential microRNA Expression in Newcastle Disease Virus-Infected HeLa Cells and Its Role in Regulating Virus Replication
por: Chen, Yu, et al.
Publicado: (2021)

Newcastle disease virus employs macropinocytosis and Rab5a-dependent intracellular trafficking to infect DF-1 cells
por: Tan, Lei, et al.
Publicado: (2016)

Exosomes Carry microRNAs into Neighboring Cells to Promote Diffusive Infection of Newcastle Disease Virus
por: Zhou, Changluan, et al.
Publicado: (2019)

Cellular vimentin regulates the infectivity of Newcastle disease virus through targeting of the HN protein
por: Lu, Xiaolong, et al.
Publicado: (2023)

Effects of the HN Antigenic Difference between the Vaccine Strain and the Challenge Strain of Newcastle Disease Virus on Virus Shedding and Transmission
por: Liu, Jingjing, et al.
Publicado: (2017)

Newcastle disease virus induces G(0)/G(1) cell cycle arrest in asynchronously growing cells
por: Wang, Yan, et al.
Publicado: (2018)

Surveillance of avirulent Newcastle disease viruses at live bird markets in Eastern China during 2008–2012 reveals a new sub-genotype of class I virus
por: Zhu, Jie, et al.
Publicado: (2014)

Entire genome sequence analysis of genotype IX Newcastle disease viruses reveals their early-genotype phylogenetic position and recent-genotype genome size
por: Qiu, Xusheng, et al.
Publicado: (2011)

SLC1A3 facilitates Newcastle disease virus replication by regulating glutamine catabolism
por: Liu, Panrao, et al.
Publicado: (2022)

MicroRNA Expression Profiling in Newcastle Disease Virus-Infected DF-1 Cells by Deep Sequencing
por: Chen, Yu, et al.
Publicado: (2019)

Phylogenetic, antigenic and biological characterization of pigeon paramyxovirus type 1 circulating in China
por: Qiu, Xusheng, et al.
Publicado: (2017)

Genome-Wide Analysis of Alternative Splicing during Host-Virus Interactions in Chicken
por: Liu, Weiwei, et al.
Publicado: (2021)

Lack of detection of host associated differences in Newcastle disease viruses of genotype VIId isolated from chickens and geese
por: Wang, Yuyang, et al.
Publicado: (2012)

eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus
por: Li, Yanrong, et al.
Publicado: (2019)

Newcastle Disease Virus Induced Pathologies Severely Affect the Exocrine and Endocrine Functions of the Pancreas in Chickens
por: Rehman, Zaib Ur, et al.
Publicado: (2021)

Chicken RNA-binding protein T-cell internal antigen-1 contributes to stress granule formation in chicken cells and tissues
por: Sun, Yingjie, et al.
Publicado: (2018)

Positive selection in the hemagglutinin-neuraminidase gene of Newcastle disease virus and its effect on vaccine efficacy
por: Gu, Min, et al.
Publicado: (2011)

Role of Macrophages in the Pathogenesis of Genotype VII Newcastle Disease Virus in Chickens
por: Ni, Jie, et al.
Publicado: (2023)

Newcastle-disease-virus-induced ferroptosis through nutrient deprivation and ferritinophagy in tumor cells
por: Kan, Xianjin, et al.
Publicado: (2021)

Gga-miR-19b-3p Inhibits Newcastle Disease Virus Replication by Suppressing Inflammatory Response via Targeting RNF11 and ZMYND11
por: Chen, Yu, et al.
Publicado: (2019)

HIV blocks Type I IFN signaling through disruption of STAT1 phosphorylation
por: Nguyen, Nam V, et al.
Publicado: (2018)

Multiplex one-step Real-time PCR by Taqman-MGB method for rapid detection of pan and H5 subtype avian influenza viruses
por: Zhang, Zhujun, et al.
Publicado: (2017)

Generation and evaluation of a recombinant genotype VII Newcastle disease virus expressing VP3 protein of Goose parvovirus as a bivalent vaccine in goslings
por: Wang, Jianzhong, et al.
Publicado: (2015)

N-linked glycosylation at site 158 of the HA protein of H5N6 highly pathogenic avian influenza virus is important for viral biological properties and host immune responses
por: Gao, Ruyi, et al.
Publicado: (2021)

Complete Genome Sequences of Two Subgenotype 1b Newcastle Disease Viruses Isolated from Sansui Sheldrake Ducks in Guizhou, China
por: Hu, Yan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_s8mf1ic6e3rpsg42cgg94g6pov