Cargando…
Upregulation of basolateral small conductance potassium channels (KCNQ1/KCNE3) in ulcerative colitis
BACKGROUND: Basolateral K(+) channels hyperpolarize colonocytes to ensure Na(+) (and thus water) absorption. Small conductance basolateral (KCNQ1/KCNE3) K(+) channels have never been evaluated in human colon. We therefore evaluated KCNQ1/KCNE3 channels in distal colonic crypts obtained from normal a...
Autores principales: | Al-Hazza, Adel, Linley, John, Aziz, Qadeer, Hunter, Malcolm, Sandle, Geoffrey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748010/ https://www.ncbi.nlm.nih.gov/pubmed/26718405 http://dx.doi.org/10.1016/j.bbrc.2015.12.086 |
Ejemplares similares
-
Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation
por: Kuenze, Georg, et al.
Publicado: (2020) -
Differential Modulations of KCNQ1 by Auxiliary Proteins KCNE1 and KCNE2
por: Li, Pan, et al.
Publicado: (2014) -
Calmodulin Antagonist W-7 Enhances Intermediate Conductance Ca(2+)- Sensitive Basolateral Potassium Channel (IK(Ca)) Activity in Human Colonic Crypts
por: Bowley, Kate A., et al.
Publicado: (2021) -
Probing the structural basis for differential KCNQ1 modulation by KCNE1 and KCNE2
por: Wang, Yuhong, et al.
Publicado: (2012) -
Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes
por: Wang, Yundi, et al.
Publicado: (2020)