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Endosialin and Associated Protein Expression in Soft Tissue Sarcomas: A Potential Target for Anti-Endosialin Therapeutic Strategies

Endosialin (CD248, TEM-1) is expressed in pericytes, tumor vasculature, tumor fibroblasts, and some tumor cells, including sarcomas, with limited normal tissue expression, and appears to play a key role in tumor-stromal interactions, including angiogenesis. Monoclonal antibodies targeting endosialin...

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Detalles Bibliográficos
Autores principales:	O'Shannessy, Daniel J., Dai, Hongyue, Mitchell, Melissa, Huntsman, Shane, Brantley, Stephen, Fenstermacher, David, Reed, Damon R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748105/ https://www.ncbi.nlm.nih.gov/pubmed/27057137 http://dx.doi.org/10.1155/2016/5213628

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