Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient

We present a patient with hepatitis C virus (HCV) and cirrhosis who was treated with eltrombopag for idiopathic thrombocytopenic purpura and was incidentally found to have a right atrial thrombus with extension into the left internal jugular vein. Eltrombopag was discontinued and the patient was tre...

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Autores principales: Baumann, Alexandra J., Wheeler, David S., Varadi, Gabor, Feyssa, Eyob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748202/
https://www.ncbi.nlm.nih.gov/pubmed/26958566
http://dx.doi.org/10.14309/crj.2016.20
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author Baumann, Alexandra J.
Wheeler, David S.
Varadi, Gabor
Feyssa, Eyob
author_facet Baumann, Alexandra J.
Wheeler, David S.
Varadi, Gabor
Feyssa, Eyob
author_sort Baumann, Alexandra J.
collection PubMed
description We present a patient with hepatitis C virus (HCV) and cirrhosis who was treated with eltrombopag for idiopathic thrombocytopenic purpura and was incidentally found to have a right atrial thrombus with extension into the left internal jugular vein. Eltrombopag was discontinued and the patient was treated with thrombectomy and anticoagulation. Given the proposed use of eltrombopag in HCV-associated thrombocytopenia, we advise caution when treating cirrhotics who are at higher intrinsic risk of thrombosis.
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spelling pubmed-47482022016-03-08 Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient Baumann, Alexandra J. Wheeler, David S. Varadi, Gabor Feyssa, Eyob ACG Case Rep J Case Report We present a patient with hepatitis C virus (HCV) and cirrhosis who was treated with eltrombopag for idiopathic thrombocytopenic purpura and was incidentally found to have a right atrial thrombus with extension into the left internal jugular vein. Eltrombopag was discontinued and the patient was treated with thrombectomy and anticoagulation. Given the proposed use of eltrombopag in HCV-associated thrombocytopenia, we advise caution when treating cirrhotics who are at higher intrinsic risk of thrombosis. American College of Gastroenterology 2016-01-20 /pmc/articles/PMC4748202/ /pubmed/26958566 http://dx.doi.org/10.14309/crj.2016.20 Text en Copyright © Baumann et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Baumann, Alexandra J.
Wheeler, David S.
Varadi, Gabor
Feyssa, Eyob
Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient
title Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient
title_full Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient
title_fullStr Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient
title_full_unstemmed Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient
title_short Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient
title_sort severe thrombotic complication of eltrombopag in a cirrhotic patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748202/
https://www.ncbi.nlm.nih.gov/pubmed/26958566
http://dx.doi.org/10.14309/crj.2016.20
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