Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis

Severe cholestasis with anabolic androgenic steroids is well-known to cause acute liver injury. Treatment is usually supportive after withdrawal of the offending agent. Acute kidney injury (AKI) frequently occurs in acute liver injury and may complicate management and prognosis. We highlight the use...

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Detalles Bibliográficos
Autores principales: Flores, Avegail, Nustas, Rosemary, Nguyen, Hoang-Lan, Rahimi, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748206/
https://www.ncbi.nlm.nih.gov/pubmed/26958570
http://dx.doi.org/10.14309/crj.2016.24
Descripción
Sumario:Severe cholestasis with anabolic androgenic steroids is well-known to cause acute liver injury. Treatment is usually supportive after withdrawal of the offending agent. Acute kidney injury (AKI) frequently occurs in acute liver injury and may complicate management and prognosis. We highlight the use of plasmapheresis resulting in rapid improvement in cholestatic jaundice with resolution of AKI. Plasmapheresis should be considered in special cases in which there is progressive clinical decline despite supportive care.

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