Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis

Severe cholestasis with anabolic androgenic steroids is well-known to cause acute liver injury. Treatment is usually supportive after withdrawal of the offending agent. Acute kidney injury (AKI) frequently occurs in acute liver injury and may complicate management and prognosis. We highlight the use...

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Autores principales: Flores, Avegail, Nustas, Rosemary, Nguyen, Hoang-Lan, Rahimi, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748206/
https://www.ncbi.nlm.nih.gov/pubmed/26958570
http://dx.doi.org/10.14309/crj.2016.24
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author Flores, Avegail
Nustas, Rosemary
Nguyen, Hoang-Lan
Rahimi, Robert S.
author_facet Flores, Avegail
Nustas, Rosemary
Nguyen, Hoang-Lan
Rahimi, Robert S.
author_sort Flores, Avegail
collection PubMed
description Severe cholestasis with anabolic androgenic steroids is well-known to cause acute liver injury. Treatment is usually supportive after withdrawal of the offending agent. Acute kidney injury (AKI) frequently occurs in acute liver injury and may complicate management and prognosis. We highlight the use of plasmapheresis resulting in rapid improvement in cholestatic jaundice with resolution of AKI. Plasmapheresis should be considered in special cases in which there is progressive clinical decline despite supportive care.
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spelling pubmed-47482062016-03-08 Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis Flores, Avegail Nustas, Rosemary Nguyen, Hoang-Lan Rahimi, Robert S. ACG Case Rep J Case Report Severe cholestasis with anabolic androgenic steroids is well-known to cause acute liver injury. Treatment is usually supportive after withdrawal of the offending agent. Acute kidney injury (AKI) frequently occurs in acute liver injury and may complicate management and prognosis. We highlight the use of plasmapheresis resulting in rapid improvement in cholestatic jaundice with resolution of AKI. Plasmapheresis should be considered in special cases in which there is progressive clinical decline despite supportive care. American College of Gastroenterology 2016-01-20 /pmc/articles/PMC4748206/ /pubmed/26958570 http://dx.doi.org/10.14309/crj.2016.24 Text en Copyright © Flores et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Flores, Avegail
Nustas, Rosemary
Nguyen, Hoang-Lan
Rahimi, Robert S.
Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis
title Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis
title_full Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis
title_fullStr Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis
title_full_unstemmed Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis
title_short Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis
title_sort severe cholestasis and bile acid nephropathy from anabolic steroids successfully treated with plasmapheresis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748206/
https://www.ncbi.nlm.nih.gov/pubmed/26958570
http://dx.doi.org/10.14309/crj.2016.24
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