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Prediction of Immunomodulatory potential of an RNA sequence for designing non-toxic siRNAs and RNA-based vaccine adjuvants

Our innate immune system recognizes a foreign RNA sequence of a pathogen and activates the immune system to eliminate the pathogen from our body. This immunomodulatory potential of RNA can be used to design RNA-based immunotherapy and vaccine adjuvants. In case of siRNA-based therapy, the immunomodu...

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Detalles Bibliográficos
Autores principales: Chaudhary, Kumardeep, Nagpal, Gandharva, Dhanda, Sandeep Kumar, Raghava, Gajendra P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748260/
https://www.ncbi.nlm.nih.gov/pubmed/26861761
http://dx.doi.org/10.1038/srep20678