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SpyRing interrogation: analyzing how enzyme resilience can be achieved with phytase and distinct cyclization chemistries
Enzymes catalyze reactions with exceptional selectivity and rate acceleration but are often limited by instability. Towards a generic route to thermo-resilience, we established the SpyRing approach, cyclizing enzymes by sandwiching between SpyTag and SpyCatcher (peptide and protein partners which lo...
Autores principales: | Schoene, Christopher, Bennett, S. Paul, Howarth, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748275/ https://www.ncbi.nlm.nih.gov/pubmed/26861173 http://dx.doi.org/10.1038/srep21151 |
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