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SpyRing interrogation: analyzing how enzyme resilience can be achieved with phytase and distinct cyclization chemistries

Enzymes catalyze reactions with exceptional selectivity and rate acceleration but are often limited by instability. Towards a generic route to thermo-resilience, we established the SpyRing approach, cyclizing enzymes by sandwiching between SpyTag and SpyCatcher (peptide and protein partners which lo...

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Detalles Bibliográficos
Autores principales: Schoene, Christopher, Bennett, S. Paul, Howarth, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748275/
https://www.ncbi.nlm.nih.gov/pubmed/26861173
http://dx.doi.org/10.1038/srep21151

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