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Inflammasome components ASC and AIM2 modulate the acute phase of biomaterial implant-induced foreign body responses

Detailing the inflammatory mechanisms of biomaterial-implant induced foreign body responses (FBR) has implications for revealing targetable pathways that may reduce leukocyte activation and fibrotic encapsulation of the implant. We have adapted a model of poly(methylmethacrylate) (PMMA) bead injecti...

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Detalles Bibliográficos
Autores principales: Christo, Susan N., Diener, Kerrilyn R., Manavis, Jim, Grimbaldeston, Michele A., Bachhuka, Akash, Vasilev, Krasimir, Hayball, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748295/
https://www.ncbi.nlm.nih.gov/pubmed/26860464
http://dx.doi.org/10.1038/srep20635