Cargando…
Complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and Marangoni microflows in centrifugally discharged droplets
We report a versatile method for the generation of complex-shaped three-dimensional multi-compartmental (3D-MC) microparticles. Complex-shaped microparticles have recently received much attention for potential application in self-assemblies, micromachines, and biomedical and environmental engineerin...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748296/ https://www.ncbi.nlm.nih.gov/pubmed/26861767 http://dx.doi.org/10.1038/srep20793 |
_version_ | 1782415102104829952 |
---|---|
author | Hayakawa, Masayuki Onoe, Hiroaki Nagai, Ken H. Takinoue, Masahiro |
author_facet | Hayakawa, Masayuki Onoe, Hiroaki Nagai, Ken H. Takinoue, Masahiro |
author_sort | Hayakawa, Masayuki |
collection | PubMed |
description | We report a versatile method for the generation of complex-shaped three-dimensional multi-compartmental (3D-MC) microparticles. Complex-shaped microparticles have recently received much attention for potential application in self-assemblies, micromachines, and biomedical and environmental engineering. Here, we have developed a method based on 3D nonequilibrium-induced microflows (Marangoni and diffusional flows) of microdroplets that are discharged from the tip of a thin capillary in a simple centrifugal microfluidic device. The microparticle shapes can be tuned by the partial dissolution of specific compartments and by the deformation of the precursor microdroplets by manipulating the 3D microflows. We believe that this method will have wide applications in nano- and microscience and technologies. |
format | Online Article Text |
id | pubmed-4748296 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-47482962016-02-17 Complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and Marangoni microflows in centrifugally discharged droplets Hayakawa, Masayuki Onoe, Hiroaki Nagai, Ken H. Takinoue, Masahiro Sci Rep Article We report a versatile method for the generation of complex-shaped three-dimensional multi-compartmental (3D-MC) microparticles. Complex-shaped microparticles have recently received much attention for potential application in self-assemblies, micromachines, and biomedical and environmental engineering. Here, we have developed a method based on 3D nonequilibrium-induced microflows (Marangoni and diffusional flows) of microdroplets that are discharged from the tip of a thin capillary in a simple centrifugal microfluidic device. The microparticle shapes can be tuned by the partial dissolution of specific compartments and by the deformation of the precursor microdroplets by manipulating the 3D microflows. We believe that this method will have wide applications in nano- and microscience and technologies. Nature Publishing Group 2016-02-10 /pmc/articles/PMC4748296/ /pubmed/26861767 http://dx.doi.org/10.1038/srep20793 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Hayakawa, Masayuki Onoe, Hiroaki Nagai, Ken H. Takinoue, Masahiro Complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and Marangoni microflows in centrifugally discharged droplets |
title | Complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and Marangoni microflows in centrifugally discharged droplets |
title_full | Complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and Marangoni microflows in centrifugally discharged droplets |
title_fullStr | Complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and Marangoni microflows in centrifugally discharged droplets |
title_full_unstemmed | Complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and Marangoni microflows in centrifugally discharged droplets |
title_short | Complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and Marangoni microflows in centrifugally discharged droplets |
title_sort | complex-shaped three-dimensional multi-compartmental microparticles generated by diffusional and marangoni microflows in centrifugally discharged droplets |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748296/ https://www.ncbi.nlm.nih.gov/pubmed/26861767 http://dx.doi.org/10.1038/srep20793 |
work_keys_str_mv | AT hayakawamasayuki complexshapedthreedimensionalmulticompartmentalmicroparticlesgeneratedbydiffusionalandmarangonimicroflowsincentrifugallydischargeddroplets AT onoehiroaki complexshapedthreedimensionalmulticompartmentalmicroparticlesgeneratedbydiffusionalandmarangonimicroflowsincentrifugallydischargeddroplets AT nagaikenh complexshapedthreedimensionalmulticompartmentalmicroparticlesgeneratedbydiffusionalandmarangonimicroflowsincentrifugallydischargeddroplets AT takinouemasahiro complexshapedthreedimensionalmulticompartmentalmicroparticlesgeneratedbydiffusionalandmarangonimicroflowsincentrifugallydischargeddroplets |