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Sorting nexin 27 interacts with Fzd7 and mediates Wnt signalling

SNX27 is the only sorting nexin (SNX) that contains a PDZ domain, which interacts with PDZ-binding motif of target proteins to regulate the trafficking of these proteins. We here showed that SNX27 interacts with Frizzled (Fzd) receptors via PDZ domain interaction. Immunofluorescence microscopy revea...

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Detalles Bibliográficos
Autores principales:	Sun, Lixiang, Hu, Xiuyong, Chen, Wanming, He, Wei, Zhang, Zhiming, Wang, Tuanlao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2016
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748333/ https://www.ncbi.nlm.nih.gov/pubmed/26744382 http://dx.doi.org/10.1042/BSR20150205

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