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COMT gene locus: new functional variants

Catechol-O-methyltransferase (COMT) metabolizes catecholaminergic neurotransmitters. Numerous studies have linked COMT to pivotal brain functions such as mood, cognition, response to stress, and pain. Both nociception and risk of clinical pain have been associated with COMT genetic variants, and thi...

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Detalles Bibliográficos
Autores principales:	Meloto, Carolina B., Segall, Samantha K., Smith, Shad, Parisien, Marc, Shabalina, Svetlana A., Rizzatti-Barbosa, Célia M., Gauthier, Josée, Tsao, Douglas, Convertino, Marino, Piltonen, Marjo H., Slade, Gary Dmitri, Fillingim, Roger B., Greenspan, Joel D., Ohrbach, Richard, Knott, Charles, Maixner, William, Zaykin, Dmitri, Dokholyan, Nikolay V., Reenilä, Ilkka, Männistö, Pekka T., Diatchenko, Luda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748386/ https://www.ncbi.nlm.nih.gov/pubmed/26207649 http://dx.doi.org/10.1097/j.pain.0000000000000273

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