Impaired nuclear factor erythroid 2-related factor 2 expression increases apoptosis of airway epithelial cells in patients with chronic obstructive pulmonary disease due to cigarette smoking

BACKGROUND: Cigarette smoking-induced oxidative stress is known to be a key mechanism in COPD pathogenesis. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a central transcription factor that regulates the antioxidant defense system. The aim of this study was to compare Nrf2 expression in COPD...

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Detalles Bibliográficos
Autores principales: Yamada, Kazuhiro, Asai, Kazuhisa, Nagayasu, Fumihiro, Sato, Kanako, Ijiri, Naoki, Yoshii, Naoko, Imahashi, Yumiko, Watanabe, Tetsuya, Tochino, Yoshihiro, Kanazawa, Hiroshi, Hirata, Kazuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748455/
https://www.ncbi.nlm.nih.gov/pubmed/26861788
http://dx.doi.org/10.1186/s12890-016-0189-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748455/
https://www.ncbi.nlm.nih.gov/pubmed/26861788
http://dx.doi.org/10.1186/s12890-016-0189-1

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