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Variations in IL-23 and IL-25 receptor gene structure, sequence and expression associated with the two disease forms of sheep paratuberculosis

The immunopathology of paucibacillary and multibacillary sheep paratuberculosis is characterized by inflammatory T cell and macrophage responses respectively. IL-23 and IL-25 are key to the development of these responses by interaction with their complex receptors, IL-23R/IL-12RB1 and IL-17RA/IL-17R...

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Detalles Bibliográficos
Autores principales: Nicol, Louise, Gossner, Anton, Watkins, Craig, Chianini, Francesca, Dalziel, Robert, Hopkins, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748472/
https://www.ncbi.nlm.nih.gov/pubmed/26861902
http://dx.doi.org/10.1186/s13567-016-0314-4