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Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis

BACKGROUND: Neuroinflammation associated with advanced human immunodeficiency virus (HIV)-1 infection is often exacerbated by chronic cocaine abuse. Cocaine exposure has been demonstrated to mediate up-regulation of inflammatory mediators in in vitro cultures of microglia. The molecular mechanisms i...

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Detalles Bibliográficos
Autores principales:	Liao, Ke, Guo, Minglei, Niu, Fang, Yang, Lu, Callen, Shannon E., Buch, Shilpa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748483/ https://www.ncbi.nlm.nih.gov/pubmed/26860188 http://dx.doi.org/10.1186/s12974-016-0501-2

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