TOPBP1 takes RADical command in recombinational DNA repair

TOPBP1 is a key player in DNA replication and DNA damage signaling. In this issue, Moudry et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507042) uncover a crucial role for TOPBP1 in DNA repair by revealing its requirement for RAD51 loading during repair of double strand breaks by homol...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Smolka, Marcus B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748579/
https://www.ncbi.nlm.nih.gov/pubmed/26811424
http://dx.doi.org/10.1083/jcb.201601028
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author Liu, Yi
Smolka, Marcus B.
author_facet Liu, Yi
Smolka, Marcus B.
author_sort Liu, Yi
collection PubMed
description TOPBP1 is a key player in DNA replication and DNA damage signaling. In this issue, Moudry et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507042) uncover a crucial role for TOPBP1 in DNA repair by revealing its requirement for RAD51 loading during repair of double strand breaks by homologous recombination.
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spelling pubmed-47485792016-08-01 TOPBP1 takes RADical command in recombinational DNA repair Liu, Yi Smolka, Marcus B. J Cell Biol Reviews TOPBP1 is a key player in DNA replication and DNA damage signaling. In this issue, Moudry et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507042) uncover a crucial role for TOPBP1 in DNA repair by revealing its requirement for RAD51 loading during repair of double strand breaks by homologous recombination. The Rockefeller University Press 2016-02-01 /pmc/articles/PMC4748579/ /pubmed/26811424 http://dx.doi.org/10.1083/jcb.201601028 Text en © 2016 Liu and Smolka This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Liu, Yi
Smolka, Marcus B.
TOPBP1 takes RADical command in recombinational DNA repair
title TOPBP1 takes RADical command in recombinational DNA repair
title_full TOPBP1 takes RADical command in recombinational DNA repair
title_fullStr TOPBP1 takes RADical command in recombinational DNA repair
title_full_unstemmed TOPBP1 takes RADical command in recombinational DNA repair
title_short TOPBP1 takes RADical command in recombinational DNA repair
title_sort topbp1 takes radical command in recombinational dna repair
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748579/
https://www.ncbi.nlm.nih.gov/pubmed/26811424
http://dx.doi.org/10.1083/jcb.201601028
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