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TOPBP1 takes RADical command in recombinational DNA repair

TOPBP1 is a key player in DNA replication and DNA damage signaling. In this issue, Moudry et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507042) uncover a crucial role for TOPBP1 in DNA repair by revealing its requirement for RAD51 loading during repair of double strand breaks by homol...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Smolka, Marcus B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748579/
https://www.ncbi.nlm.nih.gov/pubmed/26811424
http://dx.doi.org/10.1083/jcb.201601028