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The Role of HDACs as Leukemia Therapy Targets using HDI

Histone deacetylases (HDACs) are the enzymes causing deacetylation of histone and non-histone substrates. Histone deacetylase inhibitors (HDIs) are a family of drugs eliminating the effect of HDACs in malignant cells via inhibition of HDACs. Due to extensive effects upon gene expression through inte...

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Detalles Bibliográficos
Autores principales:	Ahmadzadeh, Ahmad, Khodadi, Elahe, Shahjahani, Mohammad, Bertacchini, Jessika, Vosoughi, Tina, Saki, Najmaldin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748691/ https://www.ncbi.nlm.nih.gov/pubmed/26865932

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