A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy

Extramammary Paget's disease (EMPD) is an uncommon cutaneous adenocarcinoma arising from the apocrine glands within the epidermis or underlying skin appendages in the anogenital and axillary regions. Surgical excision is basically performed as a treatment for EMPD. However, therapeutic options...

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Autores principales: Yoshihara, Yuki, Itoh, Munenari, Nobeyama, Yoshimasa, Nakagawa, Hidemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Published online: January, 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748788/
https://www.ncbi.nlm.nih.gov/pubmed/26933412
http://dx.doi.org/10.1159/000443234
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author Yoshihara, Yuki
Itoh, Munenari
Nobeyama, Yoshimasa
Nakagawa, Hidemi
author_facet Yoshihara, Yuki
Itoh, Munenari
Nobeyama, Yoshimasa
Nakagawa, Hidemi
author_sort Yoshihara, Yuki
collection PubMed
description Extramammary Paget's disease (EMPD) is an uncommon cutaneous adenocarcinoma arising from the apocrine glands within the epidermis or underlying skin appendages in the anogenital and axillary regions. Surgical excision is basically performed as a treatment for EMPD. However, therapeutic options for EMPD in an advanced stage are limited. Herein, we report the case of a Japanese woman with advanced EMPD successfully controlled by monthly but not weekly docetaxel therapy. We also demonstrate the possibility that a monthly regimen of docetaxel is a more effective and optimal schedule than a weekly one through this case report.
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spelling pubmed-47487882016-03-01 A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy Yoshihara, Yuki Itoh, Munenari Nobeyama, Yoshimasa Nakagawa, Hidemi Case Rep Oncol Published online: January, 2016 Extramammary Paget's disease (EMPD) is an uncommon cutaneous adenocarcinoma arising from the apocrine glands within the epidermis or underlying skin appendages in the anogenital and axillary regions. Surgical excision is basically performed as a treatment for EMPD. However, therapeutic options for EMPD in an advanced stage are limited. Herein, we report the case of a Japanese woman with advanced EMPD successfully controlled by monthly but not weekly docetaxel therapy. We also demonstrate the possibility that a monthly regimen of docetaxel is a more effective and optimal schedule than a weekly one through this case report. S. Karger AG 2016-01-08 /pmc/articles/PMC4748788/ /pubmed/26933412 http://dx.doi.org/10.1159/000443234 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Published online: January, 2016
Yoshihara, Yuki
Itoh, Munenari
Nobeyama, Yoshimasa
Nakagawa, Hidemi
A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy
title A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy
title_full A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy
title_fullStr A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy
title_full_unstemmed A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy
title_short A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy
title_sort case of advanced extramammary paget's disease successfully controlled by monthly but not weekly docetaxel chemotherapy
topic Published online: January, 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748788/
https://www.ncbi.nlm.nih.gov/pubmed/26933412
http://dx.doi.org/10.1159/000443234
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