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Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour
BACKGROUND: Patients with liver cirrhosis have an increased risk of developing hepatocellular carcinoma (HCC). Implantation metastasis following diagnostic biopsy is a well-known complication. Therefore, primary resection of a hypervascularised tumour suspicious for HCC is often performed with curat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger Verlag für Medizin und Naturwissenschaften GmbH
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748799/ https://www.ncbi.nlm.nih.gov/pubmed/26889148 http://dx.doi.org/10.1159/000442115 |
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author | Grambow, Eberhard Weinrich, Malte Zimpfer, Annette Kloker, Katja Klar, Ernst |
author_facet | Grambow, Eberhard Weinrich, Malte Zimpfer, Annette Kloker, Katja Klar, Ernst |
author_sort | Grambow, Eberhard |
collection | PubMed |
description | BACKGROUND: Patients with liver cirrhosis have an increased risk of developing hepatocellular carcinoma (HCC). Implantation metastasis following diagnostic biopsy is a well-known complication. Therefore, primary resection of a hypervascularised tumour suspicious for HCC is often performed with curative intent. CASE REPORT: An exophytically growing mass was diagnosed between liver segments III and IVb by means of ultrasound in a 53-year old male patient with decompensated liver cirrhosis. Computed tomography confirmed a 3.5 cm large hypervascularised tumour with given resectability. Intraoperatively, the tumour appeared like a HCC. Thus, an atypical resection was performed. Histopathology revealed ectopic spleen tissue without any signs of malignancy. As enquiries revealed, the patient had undergone splenectomy after a blunt abdominal trauma 9 years prior to admission. CONCLUSION: In the present patient, hepatic splenosis in a cirrhotic liver was misinterpreted as HCC. In patients with a history of traumatic rupture of the spleen or splenectomy, splenosis has to be considered as a potential differential diagnosis of a hypervascularised tumour. Specific diagnostics should be performed to rule out splenosis. |
format | Online Article Text |
id | pubmed-4748799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | S. Karger Verlag für Medizin und Naturwissenschaften GmbH |
record_format | MEDLINE/PubMed |
spelling | pubmed-47487992016-12-01 Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour Grambow, Eberhard Weinrich, Malte Zimpfer, Annette Kloker, Katja Klar, Ernst Viszeralmedizin Case Report BACKGROUND: Patients with liver cirrhosis have an increased risk of developing hepatocellular carcinoma (HCC). Implantation metastasis following diagnostic biopsy is a well-known complication. Therefore, primary resection of a hypervascularised tumour suspicious for HCC is often performed with curative intent. CASE REPORT: An exophytically growing mass was diagnosed between liver segments III and IVb by means of ultrasound in a 53-year old male patient with decompensated liver cirrhosis. Computed tomography confirmed a 3.5 cm large hypervascularised tumour with given resectability. Intraoperatively, the tumour appeared like a HCC. Thus, an atypical resection was performed. Histopathology revealed ectopic spleen tissue without any signs of malignancy. As enquiries revealed, the patient had undergone splenectomy after a blunt abdominal trauma 9 years prior to admission. CONCLUSION: In the present patient, hepatic splenosis in a cirrhotic liver was misinterpreted as HCC. In patients with a history of traumatic rupture of the spleen or splenectomy, splenosis has to be considered as a potential differential diagnosis of a hypervascularised tumour. Specific diagnostics should be performed to rule out splenosis. S. Karger Verlag für Medizin und Naturwissenschaften GmbH 2015-12 2015-12-02 /pmc/articles/PMC4748799/ /pubmed/26889148 http://dx.doi.org/10.1159/000442115 Text en Copyright © 2015 by S. Karger GmbH, Freiburg |
spellingShingle | Case Report Grambow, Eberhard Weinrich, Malte Zimpfer, Annette Kloker, Katja Klar, Ernst Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour |
title | Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour |
title_full | Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour |
title_fullStr | Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour |
title_full_unstemmed | Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour |
title_short | Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour |
title_sort | ectopic spleen tissue – an underestimated differential diagnosis of a hypervascularised liver tumour |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748799/ https://www.ncbi.nlm.nih.gov/pubmed/26889148 http://dx.doi.org/10.1159/000442115 |
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