Cargando…

Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour

BACKGROUND: Patients with liver cirrhosis have an increased risk of developing hepatocellular carcinoma (HCC). Implantation metastasis following diagnostic biopsy is a well-known complication. Therefore, primary resection of a hypervascularised tumour suspicious for HCC is often performed with curat...

Descripción completa

Detalles Bibliográficos
Autores principales: Grambow, Eberhard, Weinrich, Malte, Zimpfer, Annette, Kloker, Katja, Klar, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger Verlag für Medizin und Naturwissenschaften GmbH 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748799/
https://www.ncbi.nlm.nih.gov/pubmed/26889148
http://dx.doi.org/10.1159/000442115
_version_ 1782415182886076416
author Grambow, Eberhard
Weinrich, Malte
Zimpfer, Annette
Kloker, Katja
Klar, Ernst
author_facet Grambow, Eberhard
Weinrich, Malte
Zimpfer, Annette
Kloker, Katja
Klar, Ernst
author_sort Grambow, Eberhard
collection PubMed
description BACKGROUND: Patients with liver cirrhosis have an increased risk of developing hepatocellular carcinoma (HCC). Implantation metastasis following diagnostic biopsy is a well-known complication. Therefore, primary resection of a hypervascularised tumour suspicious for HCC is often performed with curative intent. CASE REPORT: An exophytically growing mass was diagnosed between liver segments III and IVb by means of ultrasound in a 53-year old male patient with decompensated liver cirrhosis. Computed tomography confirmed a 3.5 cm large hypervascularised tumour with given resectability. Intraoperatively, the tumour appeared like a HCC. Thus, an atypical resection was performed. Histopathology revealed ectopic spleen tissue without any signs of malignancy. As enquiries revealed, the patient had undergone splenectomy after a blunt abdominal trauma 9 years prior to admission. CONCLUSION: In the present patient, hepatic splenosis in a cirrhotic liver was misinterpreted as HCC. In patients with a history of traumatic rupture of the spleen or splenectomy, splenosis has to be considered as a potential differential diagnosis of a hypervascularised tumour. Specific diagnostics should be performed to rule out splenosis.
format Online
Article
Text
id pubmed-4748799
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher S. Karger Verlag für Medizin und Naturwissenschaften GmbH
record_format MEDLINE/PubMed
spelling pubmed-47487992016-12-01 Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour Grambow, Eberhard Weinrich, Malte Zimpfer, Annette Kloker, Katja Klar, Ernst Viszeralmedizin Case Report BACKGROUND: Patients with liver cirrhosis have an increased risk of developing hepatocellular carcinoma (HCC). Implantation metastasis following diagnostic biopsy is a well-known complication. Therefore, primary resection of a hypervascularised tumour suspicious for HCC is often performed with curative intent. CASE REPORT: An exophytically growing mass was diagnosed between liver segments III and IVb by means of ultrasound in a 53-year old male patient with decompensated liver cirrhosis. Computed tomography confirmed a 3.5 cm large hypervascularised tumour with given resectability. Intraoperatively, the tumour appeared like a HCC. Thus, an atypical resection was performed. Histopathology revealed ectopic spleen tissue without any signs of malignancy. As enquiries revealed, the patient had undergone splenectomy after a blunt abdominal trauma 9 years prior to admission. CONCLUSION: In the present patient, hepatic splenosis in a cirrhotic liver was misinterpreted as HCC. In patients with a history of traumatic rupture of the spleen or splenectomy, splenosis has to be considered as a potential differential diagnosis of a hypervascularised tumour. Specific diagnostics should be performed to rule out splenosis. S. Karger Verlag für Medizin und Naturwissenschaften GmbH 2015-12 2015-12-02 /pmc/articles/PMC4748799/ /pubmed/26889148 http://dx.doi.org/10.1159/000442115 Text en Copyright © 2015 by S. Karger GmbH, Freiburg
spellingShingle Case Report
Grambow, Eberhard
Weinrich, Malte
Zimpfer, Annette
Kloker, Katja
Klar, Ernst
Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour
title Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour
title_full Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour
title_fullStr Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour
title_full_unstemmed Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour
title_short Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour
title_sort ectopic spleen tissue – an underestimated differential diagnosis of a hypervascularised liver tumour
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748799/
https://www.ncbi.nlm.nih.gov/pubmed/26889148
http://dx.doi.org/10.1159/000442115
work_keys_str_mv AT gramboweberhard ectopicspleentissueanunderestimateddifferentialdiagnosisofahypervascularisedlivertumour
AT weinrichmalte ectopicspleentissueanunderestimateddifferentialdiagnosisofahypervascularisedlivertumour
AT zimpferannette ectopicspleentissueanunderestimateddifferentialdiagnosisofahypervascularisedlivertumour
AT klokerkatja ectopicspleentissueanunderestimateddifferentialdiagnosisofahypervascularisedlivertumour
AT klarernst ectopicspleentissueanunderestimateddifferentialdiagnosisofahypervascularisedlivertumour