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Structural and functional insights into the fly microRNA biogenesis factor Loquacious

In the microRNA (miRNA) pathway, Dicer processes precursors to mature miRNAs. For efficient processing, double-stranded RNA-binding proteins support Dicer proteins. In flies, Loquacious (Loqs) interacts with Dicer1 (dmDcr1) to facilitate miRNA processing. Here, we have solved the structure of the th...

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Detalles Bibliográficos
Autores principales:	Jakob, Leonhard, Treiber, Thomas, Treiber, Nora, Gust, Alexander, Kramm, Kevin, Hansen, Kerrin, Stotz, Mathias, Wankerl, Ludwig, Herzog, Franz, Hannus, Stefan, Grohmann, Dina, Meister, Gunter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748816/ https://www.ncbi.nlm.nih.gov/pubmed/26769856 http://dx.doi.org/10.1261/rna.055426.115

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