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The impact of including corticosteroid in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial
There is conflicting evidence about the benefit of using corticosteroid in periarticular injections for pain relief after total knee arthroplasty (TKA). We carried out a double-blinded, randomised controlled trial to assess the efficacy of using corticosteroid in a periarticular injection to control...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
British Editorial Society of Bone and Joint Surgery
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748830/ https://www.ncbi.nlm.nih.gov/pubmed/26850424 http://dx.doi.org/10.1302/0301-620X.98B2.36596 |
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author | Tsukada, S. Wakui, M. Hoshino, A. |
author_facet | Tsukada, S. Wakui, M. Hoshino, A. |
author_sort | Tsukada, S. |
collection | PubMed |
description | There is conflicting evidence about the benefit of using corticosteroid in periarticular injections for pain relief after total knee arthroplasty (TKA). We carried out a double-blinded, randomised controlled trial to assess the efficacy of using corticosteroid in a periarticular injection to control pain after TKA. A total of 77 patients, 67 women and ten men, with a mean age of 74 years (47 to 88) who were about to undergo unilateral TKA were randomly assigned to have a periarticular injection with or without corticosteroid. The primary outcome was post-operative pain at rest during the first 24 hours after surgery, measured every two hours using a visual analogue pain scale score. The cumulative pain score was quantified using the area under the curve. The corticosteroid group had a significantly lower cumulative pain score than the no-corticosteroid group during the first 24 hours after surgery (mean area under the curve 139, 0 to 560, and 264, 0 to 1460; p = 0.024). The rate of complications, including surgical site infection, was not significantly different between the two groups up to one year post-operatively. The addition of corticosteroid to the periarticular injection significantly decreased early post-operative pain. Further studies are needed to confirm the safety of corticosteroid in periarticular injection. Take home message: The use of corticosteroid in periarticular injection offered better pain relief during the initial 24 hours after TKA. Cite this article: Bone Joint J 2016;98-B:194–200. |
format | Online Article Text |
id | pubmed-4748830 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | British Editorial Society of Bone and Joint Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-47488302016-03-01 The impact of including corticosteroid in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial Tsukada, S. Wakui, M. Hoshino, A. Bone Joint J Knee There is conflicting evidence about the benefit of using corticosteroid in periarticular injections for pain relief after total knee arthroplasty (TKA). We carried out a double-blinded, randomised controlled trial to assess the efficacy of using corticosteroid in a periarticular injection to control pain after TKA. A total of 77 patients, 67 women and ten men, with a mean age of 74 years (47 to 88) who were about to undergo unilateral TKA were randomly assigned to have a periarticular injection with or without corticosteroid. The primary outcome was post-operative pain at rest during the first 24 hours after surgery, measured every two hours using a visual analogue pain scale score. The cumulative pain score was quantified using the area under the curve. The corticosteroid group had a significantly lower cumulative pain score than the no-corticosteroid group during the first 24 hours after surgery (mean area under the curve 139, 0 to 560, and 264, 0 to 1460; p = 0.024). The rate of complications, including surgical site infection, was not significantly different between the two groups up to one year post-operatively. The addition of corticosteroid to the periarticular injection significantly decreased early post-operative pain. Further studies are needed to confirm the safety of corticosteroid in periarticular injection. Take home message: The use of corticosteroid in periarticular injection offered better pain relief during the initial 24 hours after TKA. Cite this article: Bone Joint J 2016;98-B:194–200. British Editorial Society of Bone and Joint Surgery 2016-02-01 /pmc/articles/PMC4748830/ /pubmed/26850424 http://dx.doi.org/10.1302/0301-620X.98B2.36596 Text en ©2016 Tsukada et al This is an open-access article distributed under the terms of the Creative Commons Attributions licence (CC-BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, but not for commercial gain, provided the original author and source are credited. |
spellingShingle | Knee Tsukada, S. Wakui, M. Hoshino, A. The impact of including corticosteroid in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial |
title | The impact of including corticosteroid
in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial |
title_full | The impact of including corticosteroid
in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial |
title_fullStr | The impact of including corticosteroid
in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial |
title_full_unstemmed | The impact of including corticosteroid
in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial |
title_short | The impact of including corticosteroid
in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial |
title_sort | impact of including corticosteroid
in a periarticular injection for pain control after total knee arthroplasty: a double-blind randomised controlled trial |
topic | Knee |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748830/ https://www.ncbi.nlm.nih.gov/pubmed/26850424 http://dx.doi.org/10.1302/0301-620X.98B2.36596 |
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