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Pharmacokinetic/Toxicity Properties of the New Anti-Staphylococcal Lead Compound SK-03-92
Because of the potential of a new anti-staphylococcal lead compound SK-03-92 as a topical antibiotic, a patch, or an orally active drug, we sought to determine its safety profile and oral bioavailability. SK-03-92 had a high IC(50) (125 μg/mL) in vitro against several mammalian cell lines, and mice...
Autores principales: | Schwan, William R., Kolesar, Jill M., Kabir, M. Shahjahan, Elder, Edmund J., Williams, Jeffrey B., Minerath, Rachel, Cook, James M., Witzigmann, Christopher M., Monte, Aaron, Flaherty, Tricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748848/ https://www.ncbi.nlm.nih.gov/pubmed/26877886 http://dx.doi.org/10.3390/antibiotics4040617 |
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