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Differential Effects of Bariatric Surgery Versus Exercise on Excessive Visceral Fat Deposits
The aim of the present study was to compare differential impacts of bariatric surgery and exercise-induced weight loss on excessive abdominal and cardiac fat deposition. Excessive fat accumulation around the heart may play an important role in the pathogenesis of cardiovascular disease. Recent evide...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748890/ https://www.ncbi.nlm.nih.gov/pubmed/26844473 http://dx.doi.org/10.1097/MD.0000000000002616 |
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author | Wu, Fu-Zong Huang, Yi-Luan Wu, Carol C. Wang, Yen-Chi Pan, Hsiang-Ju Huang, Chin-Kun Yeh, Lee-Ren Wu, Ming-Ting |
author_facet | Wu, Fu-Zong Huang, Yi-Luan Wu, Carol C. Wang, Yen-Chi Pan, Hsiang-Ju Huang, Chin-Kun Yeh, Lee-Ren Wu, Ming-Ting |
author_sort | Wu, Fu-Zong |
collection | PubMed |
description | The aim of the present study was to compare differential impacts of bariatric surgery and exercise-induced weight loss on excessive abdominal and cardiac fat deposition. Excessive fat accumulation around the heart may play an important role in the pathogenesis of cardiovascular disease. Recent evidences have suggested that bariatric surgery results in relatively less decrease in epicardial fat compared with abdominal visceral fat and paracardial fat. Sixty-four consecutive overweight or obese subjects were enrolled in the study. Clinical characteristics and metabolic profiles were recorded. The volumes of abdominal visceral adipose tissue (AVAT), abdominal subcutaneous adipose tissue (ASAT), epicardial (EAT), and paracardial adipose tissue (PAT) were measured by computed tomography in the bariatric surgery group (N = 25) and the exercise group (N = 39) at baseline and 3 months after intervention. Subjects in both the surgery and exercise groups showed significant reduction in body mass index (15.97%, 7.47%), AVAT (40.52%, 15.24%), ASAT (31.40, 17.34%), PAT (34.40%, 12.05%), and PAT + EAT (22.31%, 17.72%) (all P < 0.001) after intervention compared with baseline. In both the groups, the decrease in EAT was small compared with the other compartments (P < 0.01 in both groups). Compared with the exercise group, the surgery group had greater loss in abdominal and cardiac visceral adipose tissue (AVAT, ASAT, PAT, EAT+PAT) (P < 0.001), but lesser loss in EAT (P = 0.037). Compared with the exercise group, bariatric surgery results in significantly greater percentage loss of excessive fat deposits except for EAT. EAT, but not PAT, was relatively preserved despite weight reduction in both the groups. The physiological impact of persistent EAT deserves further investigation. |
format | Online Article Text |
id | pubmed-4748890 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-47488902016-04-01 Differential Effects of Bariatric Surgery Versus Exercise on Excessive Visceral Fat Deposits Wu, Fu-Zong Huang, Yi-Luan Wu, Carol C. Wang, Yen-Chi Pan, Hsiang-Ju Huang, Chin-Kun Yeh, Lee-Ren Wu, Ming-Ting Medicine (Baltimore) 3900 The aim of the present study was to compare differential impacts of bariatric surgery and exercise-induced weight loss on excessive abdominal and cardiac fat deposition. Excessive fat accumulation around the heart may play an important role in the pathogenesis of cardiovascular disease. Recent evidences have suggested that bariatric surgery results in relatively less decrease in epicardial fat compared with abdominal visceral fat and paracardial fat. Sixty-four consecutive overweight or obese subjects were enrolled in the study. Clinical characteristics and metabolic profiles were recorded. The volumes of abdominal visceral adipose tissue (AVAT), abdominal subcutaneous adipose tissue (ASAT), epicardial (EAT), and paracardial adipose tissue (PAT) were measured by computed tomography in the bariatric surgery group (N = 25) and the exercise group (N = 39) at baseline and 3 months after intervention. Subjects in both the surgery and exercise groups showed significant reduction in body mass index (15.97%, 7.47%), AVAT (40.52%, 15.24%), ASAT (31.40, 17.34%), PAT (34.40%, 12.05%), and PAT + EAT (22.31%, 17.72%) (all P < 0.001) after intervention compared with baseline. In both the groups, the decrease in EAT was small compared with the other compartments (P < 0.01 in both groups). Compared with the exercise group, the surgery group had greater loss in abdominal and cardiac visceral adipose tissue (AVAT, ASAT, PAT, EAT+PAT) (P < 0.001), but lesser loss in EAT (P = 0.037). Compared with the exercise group, bariatric surgery results in significantly greater percentage loss of excessive fat deposits except for EAT. EAT, but not PAT, was relatively preserved despite weight reduction in both the groups. The physiological impact of persistent EAT deserves further investigation. Wolters Kluwer Health 2016-02-08 /pmc/articles/PMC4748890/ /pubmed/26844473 http://dx.doi.org/10.1097/MD.0000000000002616 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0 |
spellingShingle | 3900 Wu, Fu-Zong Huang, Yi-Luan Wu, Carol C. Wang, Yen-Chi Pan, Hsiang-Ju Huang, Chin-Kun Yeh, Lee-Ren Wu, Ming-Ting Differential Effects of Bariatric Surgery Versus Exercise on Excessive Visceral Fat Deposits |
title | Differential Effects of Bariatric Surgery Versus Exercise on Excessive Visceral Fat Deposits |
title_full | Differential Effects of Bariatric Surgery Versus Exercise on Excessive Visceral Fat Deposits |
title_fullStr | Differential Effects of Bariatric Surgery Versus Exercise on Excessive Visceral Fat Deposits |
title_full_unstemmed | Differential Effects of Bariatric Surgery Versus Exercise on Excessive Visceral Fat Deposits |
title_short | Differential Effects of Bariatric Surgery Versus Exercise on Excessive Visceral Fat Deposits |
title_sort | differential effects of bariatric surgery versus exercise on excessive visceral fat deposits |
topic | 3900 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748890/ https://www.ncbi.nlm.nih.gov/pubmed/26844473 http://dx.doi.org/10.1097/MD.0000000000002616 |
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