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Ultracentrifugation-free chromatography-mediated large-scale purification of recombinant adeno-associated virus serotype 1 (rAAV1)

Recombinant adeno-associated virus (rAAV) is an attractive tool for gene transfer and shows potential for use in human gene therapies. The current methods for the production and purification of rAAV from the transfected cell lysate are mainly based on cesium chloride and iodixanol density ultracentr...

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Detalles Bibliográficos
Autores principales:	Tomono, Taro, Hirai, Yukihiko, Okada, Hironori, Adachi, Kumi, Ishii, Akiko, Shimada, Takashi, Onodera, Masafumi, Tamaoka, Akira, Okada, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748944/ https://www.ncbi.nlm.nih.gov/pubmed/26913289 http://dx.doi.org/10.1038/mtm.2015.58

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