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Simvastatin Sodium Salt and Fluvastatin Interact with Human Gap Junction Gamma-3 Protein

Finding pleiomorphic targets for drugs allows new indications or warnings for treatment to be identified. As test of concept, we applied a new chemical genomics approach to uncover additional targets for the widely prescribed lipid-lowering pro-drug simvastatin. We used mRNA extracted from internal...

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Detalles Bibliográficos
Autores principales:	Marsh, Andrew, Casey-Green, Katherine, Probert, Fay, Withall, David, Mitchell, Daniel A., Dilly, Suzanne J., James, Sean, Dimitri, Wade, Ladwa, Sweta R., Taylor, Paul C., Singer, Donald R. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749215/ https://www.ncbi.nlm.nih.gov/pubmed/26863535 http://dx.doi.org/10.1371/journal.pone.0148266

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