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Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules
RIG-I triggers antiviral responses by recognizing viral RNA (vRNA) in the cytoplasm. However, the spatio-temporal dynamics of vRNA sensing and signal transduction remain elusive. We investigated the time course of events in cells infected with Newcastle disease virus (NDV), a non-segmented negative-...
Autores principales: | Oh, Seong-Wook, Onomoto, Koji, Wakimoto, Mai, Onoguchi, Kazuhide, Ishidate, Fumiyoshi, Fujiwara, Takahiro, Yoneyama, Mitsutoshi, Kato, Hiroki, Fujita, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749238/ https://www.ncbi.nlm.nih.gov/pubmed/26862753 http://dx.doi.org/10.1371/journal.ppat.1005444 |
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