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High-Field MRI Reveals a Drastic Increase of Hypoxia-Induced Microhemorrhages upon Tissue Reoxygenation in the Mouse Brain with Strong Predominance in the Olfactory Bulb

Human pathophysiology of high altitude hypoxic brain injury is not well understood and research on the underlying mechanisms is hampered by the lack of well-characterized animal models. In this study, we explored the evolution of brain injury by magnetic resonance imaging (MRI) and histological meth...

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Detalles Bibliográficos
Autores principales: Hoffmann, Angelika, Kunze, Reiner, Helluy, Xavier, Milford, David, Heiland, Sabine, Bendszus, Martin, Pham, Mirko, Marti, Hugo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749302/
https://www.ncbi.nlm.nih.gov/pubmed/26863147
http://dx.doi.org/10.1371/journal.pone.0148441